Pleural mesothelioma
Pleural mesothelioma is pleural mesothelioma primary tumor, there are localized (mostly benign) and diffuse (all malignant) of the sub. One type of diffuse malignant mesothelioma is a chest tumor one of the worst prognosis. The majority of patients between the ages of 40-70, more men than women.The first symptom to chest pain, shortness of breath and coughing the most common. To have fever, sweating or joint pain mainly v. symptoms. About half of patients over a large number of pleural effusion with severe shortness of breath. A large number of those without pleural effusion often more severe chest pain, weight loss common.Ordinary X-ray revealed pleural effusion, while lung tumor tissue was wrapped, and so on, have advanced cases of pericardial effusion caused by the heart shadow and the expansion of soft tissue damage, such as video and ribs. Suspicious for malignant pleural mesothelioma patients, CT examination of the most useful. Pleural effusion cytology also contribute to the diagnosis. Conventional laboratory tests, some patients may have a number of platelets, serum carcinoembryonic antigen (CEA), and so increased. For routine inspection diagnosis is not entirely clear, can be used to do thoracoscopic pleural biopsy. In general most patients can not obtain a diagnosis.
The treatment of malignant pleural mesothelioma, is still no effective cure method. Treatment, a palliative treatment, surgical treatment, chemotherapy and radiation treatment, the tumor is generally believed that the relatively limited period I patients, so that solution to the problem of pleural pneumonectomy. For â…¡, â…¢, â…£ phase patients, radical surgery has no meaning, only the implementation of palliative operation. In fact, the majority of patients to a clear diagnosis of the disease, is in Phase II or more. The rapid growth of patients with pleural effusion often leads to serious breathing difficulties, the palliative operation for the terminally ill to improve their quality of life is of great significance. In the past the use of chemotherapy drugs into the chest cavity, such as regression to pleural effusion, or adhesion of the closed method often difficult to be effective. I introduced thoracoscopic pleurodesis, malignant pleural mesothelioma in the palliative treatment achieved good results, assisted thoracic surgery pleural aspiration will be able to complete a clean, and full separation of adhesion, so that the lung, and then injected into Talcum powder disinfectant, pleurodesis, have control of pleural effusion, in patients with advanced cancer to alleviate the symptoms. We have a simple home-made powder spray device with a convenient and practical, effective, and other characteristics of the spray has been widely used by domestic counterparts, combined with our many years of experience in thoracic surgery, so I Division in the treatment of malignant pleural mesothelioma reached on Domestic and international advanced level.
Overview: Pleural mesothelioma (Department of Respiratory Medicine) for the primary pleural tumor, is from the dirty floor, wall, or diaphragm mediastinal pleura four parts of the tumor. Foreign higher than the incidence of domestic, to 0.07 to 0.11 percent and 0.04 percent. Mortality rate in the world accounting for all of the tumors less than 1%. In recent years, there is obviously on the rise. Often more than 50-year-old, male to female ratio was 2:1. With asbestos-related contacts. At present, there is no vicious-effective treatment.
Symptoms:
1. Localized can be no discomfort or only chest pain, shortness of breath after the activity.2. Diffuse than those who have severe chest pain, shortness of breath, weight loss, and so on. 3. Thorax side restricted activity, full, percussion dullness, to reduce the Respiratory sound or disappear. 4. Supraclavicular have lymph nodes under the arms and Waterloo.
Diagnosis based on:
1. Chest pain, shortness of breath, suffering from weight loss and other symptoms. 2. Pleural effusions and pleural thickening of the signs.3. Chest CT see the chest or pleural nodules. 4. Thoracoscopy nodules can be seen and can clamp the activities of the organization take a clear diagnosis of the cause.
Treatment:
Treatment should be limited-surgical treatment of choice, can diffuse combination of surgery and chemotherapy.
The principle of a drug. There are those with chest pain rotundine, indomethacin, dolantin pain, and so on. 2. Doxorubicin is an effective drug treatment of this disease, with cisplatin, mitomycin C, cyclophosphamide, methotrexate, such as the use of the joint.3.γ-interferon, IL-measures as adjuvant therapy. 4. Effusion were more than talcum powder can be used, such as tetracycline for pleural adhesions.
Prevention of common sense:
Pleural mesothelioma, regular contact with asbestos, so pay attention to labor protection and reduce or avoid contact with asbestos is an effective disease prevention measures. For the more limited type of benign, surgical treatment effective; even if it is malignant diffuse, be used to adriamycin-based chemotherapy can also be achieved positive results, significantly extend survival time.
